WHAT ARE PHEROMONES?
Pheromones are natural, odorless and consciously undetectable substances, which trigger a deep sexual response in the brain of those who come into contact with them. The pheromone related to human sexual attraction is androstadienone. The production and secretion of pheromones are natural processes regulated by hormones and stimuli from nervous system, which arrive to cells of apocrine glands and sebocytes of sebaceous glands.
HOW DOES IT WORK?
Diterpene obtained from makandi root (Coleus forskohlii).
Increases the expression of the enzyme 3ß-HSD to produce more androstadienone
Polyphenols obtained from black tea leaves (Camellia sinensis).
Reduce 5α-reductase activity to decrease androstadienone metabolization and cause its accumulation
IN VITRO EFFICACY
Development of an Innovative Cellular Model
The creation of a suitable cellular model able to produce pheromones was necessary to evaluate our product in vitro efficacy.
Progenitor keratinocytes, which can differentiate to sebocytes under certain conditions, were selected. Originated sebocytes were identified,
characterized and they showed their ability to produce pheromones, especially androstadienone.
Boosting effect of androstadienone production
The complementary actions of forskolin and theaflavins lead to a boosting synergistic effect.
Our product doubles the production of androstadienone (105%) at a concentration of 1.2%.
The amount of pheromone increases in parallel to the concentration,
reaching three times the control result at the maximum dosage (5%).